孟鲁司特钠在儿童医院门诊的使用情况分析

Analysis of Montelukast Sodium Application in Outpatient Department of Children′s Hospital

目的:分析我院门诊孟鲁司特钠的使用情况,为临床合理用药提供参考和建议。方法:抽取我院门诊药房2020年1~6月对有孟鲁司特钠的处方进行回顾性分析,对处方中患者年龄、剂型剂量、临床诊断进行分类统计分析。结果:收集门诊含孟鲁司特钠的有效处方共8193份。患者年龄以2-5岁居多,6个月以下患儿占0.71%;多数给予4mg的咀嚼片,约有2.58%超剂量给药,3.89%剂量不足;该药在门诊主要用于呼吸道感染、哮喘、鼻炎等疾病的治疗。我院门诊孟鲁司特钠的使用存在超说明书用药和过度用药问题。结论:应注意孟鲁司特钠的使用时机,根据患儿年龄为其选择合适的剂型剂量,保障临床儿童用药安全、有效、经济。

Objective:To analyze the application of montelukast sodium in outpatients from our hospital,so as to provide references for clinical rational use of drug.Methods:The prescriptions containing montelukast sodium application in outpatient department of our Hospital from January to June in 2020 were extracted by systematic sampling.Patients′age,drug dosage and formulations and indication classified statistically.Results:Totally,there were 8193 pieces of prescription available.Montelukast sodium was mostly used for children aged 2 to 5 years old.There were about 0.71 percent of patients who were younger than six months.It′s worth noting that montelukast sodium was not approved for infant below six months.The dosage in our research was mainly 4 mg,chewable tablets.Among all the prescription,there was about 2.58 percent of patients overdose and 3.89 percent of patients underdose.Montelukast sodium was mainly used for treating diseases of respiratory infection,asthma and rhinitis.Conclusion:There were some unreasonable application of montelukast sodium in our hospital,such as off-label use and overprescribing of medicines.Clinical application should pay more attention to indication.We should choose the more appropriate dosage and formulation for children according to their age,so as to ensure the safety,effectiveness and economy of medication.