正念干预对癌症患者创伤后成长干预效果的meta分析

A meta-analysis of effect of mindfulness-based intervention on posttraumatic growth in patients with cancer

目的:评价正念干预(MBI)对癌症患者创伤后成长(PTG)的干预效果。方法:计算机检索Cochrane library、PubMed、Embase、Web of Science、CBM、VIP、WangFang Data和CNKI数据库中MBI对癌症患者PTG的随机对照试验(RCT)。两名研究者按照纳入排除标准独立筛选文献、进行文献质量评价并从中提取数据,采用RevMan 5.3软件进行数据分析。结果:共纳入9篇RCT,合计822例患者。Meta分析结果显示,实施MBI后,干预组患者的PTG水平优于对照组,差异有统计学意义[MD=7.27,95%CI=(4.75~9.79),P<0.001],干预效果能维持到干预后3个月[MD=8.64,95%CI=(7.20~10.08),P<0.001]。与对照组相比,线上干预模式对癌症患者PTG的改善效果不明显,差异无统计学意义[MD=3.59,95%CI=(-1.22~8.41),P>0.05],而面对面的小组干预模式能促进癌症患者PTG水平的提高[MD=7.87,95%CI=(5.19~10.54),P<0.001]。结论:正念干预有助于提高癌症患者的创伤后成长水平,面对面小组干预模式比线上干预模式在提升患者的创伤后成长水平上效果更佳。

Objective:To evaluate the effect of mindfulness-based intervention(MBI)on posttraumatic growth(PTG)in patients with cancer.Methods:The randomized controlled trial(RCT)literatures on the effect of MBI on PTG in patients with cancer were retrieved from Cochrane library,PubMed,Embase,Web of Science,CBM,VIP,WangFang Data and CNKI.Two investigators independently screened the studies,extracted data,and performed quality assessment using the Cochrane risk of bias assessment tool.Meta-analyses were conducted with RevMan 5.3 software.Results:Nine studies were included with a total of 822 participants.Those who received MBI reported significantly higher PTG than respondents in control groups immediately after intervention[MD=7.27,95%CI=(4.75-9.79),P<0.001],and the effect could be maintained until 3 months after intervention[MD=8.64,95%CI=(7.20-10.08),P<0.001].The online intervention model had no significant effect on PTG compared with the control group[MD=3.59,95%CI=(-1.22-8.41),P>0.05],while the face-to-face group intervention model was beneficial[MD=7.87,95%CI=(5.19-10.54),P<0.001].Conclusion:It suggests that mindfulness-based interventions could effectively promote the posttraumatic growth level of patients with cancer,and the face-to-face group intervention model is more effective than the online intervention model.