8例替加环素致低钙血症不良反应分析

Eight Cases of Hypocalcemia Induced by Tigecycline

目的提高临床使用替加环素的安全性。方法借助于某三甲医院2018年7月1日至2019年6月30日不良反应主动监测软件筛选使用替加环素发生低钙血症的患者,结合电子病历和药品不良反应判定标准对数据进行分析。结果使用替加环素与发生低钙血症相关。结论建议临床使用替加环素时,应加强对血钙的监测。

Objective To improve the safety of clinical use of tigecycline.Methods Patients with hypocalcemia caused by tigecycline were screened from July 1,2018 to June 30,2019 with active monitoring software for adverse reactions before data was analyzed using electronic medical records and adverse reaction criteria.Results The use of tigecycline was associated with hypocalcemia.Conclusion It is recommended that the monitoring of serum calcium be enhanced when tigecycline is used in clinic.