1例直肠癌患者新辅助化疗发生肺栓塞的药学干预实践

Pharmaceutical Intervention for Pulmonary Embolism in a Rectal Cancer Patient Treated with New Assisted Chemotherapy

目的介绍贝伐珠单抗致肺栓塞的药学实践。方法临床药师通过查阅文献及相关指南,对1例贝伐珠单抗联合化疗致肺栓塞不良反应进行评估,结合患者病情及意愿对抗凝药物选择提供建议及监护。结果临床药师提出药品不良反应处理方案,医师采纳建议,患者肺栓塞控制良好。结论临床药师与医师合作,以患者为中心,保障患者用药安全,为临床合理用药提供参考。

Objective To introduce the pharmaceutical disposal one case of pulmonary embolism induced by bevacizumab.Methods Two clinical pharmacists participated in the evaluation of adverse reactions of pulmonary embolism induced by bevacizumab in combination with chemotherapy by consulting related literature and guidelines.Based on the patient's condition and willingness,the pharmacist gave advice on the selection of anticoagulants.Results The clinical pharmacists recommended solutions to the ADR,the physician adopted the recommendation,the patient's pulmonary embolish was well controlled.Conclusion Clinical pharmacists are expected to cooperate with clinicians,give a top priority to the safety of patients and give advice on clinical rational drug use.