PCT、WBC及CRP联合检测对新生儿败血症的诊疗意义

PCT,WBC and CRP Clinical Significance for the Diagnosis and Treatment of Neonatal Aepsis

目的分析在诊疗新生儿败血症疾病中应用C反应蛋白(C-reactive protein,CRP)、降钙素原(procalcitonin,PCT)及白细胞(leukocyte,white blood cell,WBC)联合检测的意义。方法对我院在2017年1月—2019年1月收治的80例新生儿败血症患儿进行研究,将PCT、WBC及CRP联合检测的灵敏度与PCT+WBC和WBC+CRP检测灵敏度对比,分析在诊疗新生儿败血症疾病中应用PCT、WBC及CRP联合检测的意义。结果经过治疗后患儿PCT、WBC及CRP指标得到下降,患儿临床症状得到极大缓解,且PCT、WBC及CRP三项联合检测的灵敏度28.75%、高于PCT、WBC联合检测灵敏度13.75%和WBC及CRP联合检测灵敏度25.00%。结论在诊疗新生儿败血症疾病中应用PCT、WBC及CRP联合检测具备一定的有效性。

Objective To analyze the significance of combined detection of C-reactive protein(CRP),procalcitonin(PCT)and white blood cell(WBC)in the diagnosis and treatment of neonatal sepsis.Methods 80 cases of neonatal septicemia in our hospital from January 2017 to January 2019 were studied.The sensitivity of combined detection of PCT,WBC and CRP was compared with that of PCT+WBC and WBC+CRP.The significance of combined detection of PCT,WBC and CRP in the diagnosis and treatment of neonatal septicemia was analyzed.Results After treatment,the indexes of PCT,WBC and CRP were decreased,and the clinical symptoms were greatly relieved.The sensitivity of combined detection of PCT,WBC and CRP was 28.75%,which was higher than that of combined detection of PCT and WBC by 13.75%and combined detection of WBC and CRP by 25.00%.Conclusion The combined detection of PCT,WBC and CRP is effective in the diagnosis and treatment of neonatal sepsis.