摘要
动脉导管未闭(PDA)是严重影响新生儿尤其是早产儿存活及生存质量的一种疾病。目前针对PDA的治疗仍存在很大争议。本文介绍了近年来关于PDA的治疗时机选择、治疗方式(内科治疗、手术结扎及预防性治疗)及药物选择(吲哚美辛、布洛芬及对乙酰氨基酚)的研究进展,并对其利弊进行分析。
Patent ductus arteriosus(PDA)is a disease that seriously affects the survival and quality of neonates,especially for premature infants.The treatment of PDA,however,is still controversial.This review introduces the research progress in the treatment of timing,methods(medical treatment,surgical ligation and preventive treatment)and drug selection(indomethacin,ibuprofen and paracetamol)of PDA in recent years,and analyzes their advantages and disadvantages.
作者
赵颖
田秀英
边希云
张婉娴
ZHAO Ying;TIAN Xiu-ying;BIAN Xi-yun;ZHANG Wan-xian(Department of Neonatology,Tianjin Central Hospital of Gynecology and Obstetrics,Tianjin 300100,China;Central Laboratory of Tianjin Fifth Central Hospital,Tianjin Key Laboratory of Epigenetics of Organ Development of Premature Infants)
出处
《天津医药》
CAS
北大核心
2021年第1期103-107,共5页
Tianjin Medical Journal
基金
国家自然科学基金青年科学基金项目(81901526)。
关键词
动脉导管未闭
吲哚美辛
布洛芬
醋氨酚
结扎术
婴儿
新生
疾病
ductus arteriosus,patent
indomethacin
ibuprofen
acetaminophen
ligation
infant,newborn,diseases
