从“气脉常通”论血管稳态失衡及理气活血论治内涵

Discussed the Imbalance of Vascular Homeostasis and Therapeutic Method Base on the Theories of"Qimai Changtong"and"Li Qi Huo Xue"

血管稳态是指血管内环境的相对稳定,维持正常结构与功能的一种理想状态。本文提出从中医“气脉常通”来认识血管稳态,血管稳态的维持与“气脉”的通达与否关系密切。血管稳态失衡所表现的血管内皮结构及功能损伤、炎症反应、斑块形成、管腔狭窄等与“气脉”功能障碍导致的“气病脉阻”相关。“气病”是导致血管稳态失衡的基础,是导致“脉阻”的关键,“脉阻”是导致动脉粥样硬化发生发展的决定性因素,“理气活血”治法是防治的重要原则。多靶点、多途径维持血管稳态,干预血管稳态失衡是现今预防心血管疾病发生发展的新方向。文章初步探讨“理气活血”治法论治血管稳态失衡,为临床防治动脉粥样硬化类疾病提供新思路。

Vascular homeostasis refers to an ideal state in which the intravascular environment is relatively stable and maintains normal structure and function.This paper proposes to understand the vascular homeostasis from the traditional Chinese medicine"air and pulse",and the maintenance of vascular homeostasis is closely related to the accessibility of"Qimai".Vascular endothelial structural and functional impairment,inflammatory response,plaque formation,and luminal stenosis,which are manifested by vascular homeostasis,are associated with"Qi disease variability"caused by"Qimai"dysfunction."Gas disease"is the basis for the imbalance of vascular homeostasis,and is the key to cause"pulsation",which is the decisive factor leading to the development of atherosclerosis.The principle of"Li Qi Huo Xue"is an important rule for prevention and treatment.Multi-target,multi-channel maintenance of vascular homeostasis,intervention of vascular homeostasis is a new direction to prevent the occurrence and development of cardiovascular disease.The article preliminary discusses the treatment of qi and blood circulation to treat vascular homeostasis imbalance,and provides new ideas for clinical prevention and treatment of atherosclerotic diseases.