2012-2018年重庆市脑出血发病及死亡趋势分析

Trend analysis of intracerebral hemorrhage from 2012 to 2018 in Chongqing Municipality

目的了解重庆市脑出血发病及死亡趋势变化,为开展脑出血防治提供参考。方法2012-2018年重庆市脑出血(ICD-10:I61~I62)个案资料来源于中国疾病预防控制中心国家心脑血管事件登记报告系统,采用SPSS 25.0统计分析发病率、标化发病率、死亡率、标化死亡率、构成比。不同地区、不同性别人群脑出血发病率与死亡率的比较采用χ2检验。率的趋势变化采用年度变化百分比(APC)分析。结果脑出血发病率与标化发病率2012年分别为70.87/10万、59.04/10万,2018年分别为78.15/10万、60.44/10万。脑出血发病率与标化发病率分别以年均4.39%与3.67%的比例上升,变化趋势差异无统计学意义(均P>0.05)。脑出血死亡率男性均高于女性,差异有统计学意义(均P<0.05)。郊县居民脑出血发病率高于主城,差异均有统计学意义(均P<0.05)。脑出血死亡率由2012年的58.78/10万上升至2018年的69.84/10万,年均增长率为3.77%,变化趋势差异有统计学意义(t=4.38,P=0.007),脑出血标化死亡率2012年与2018年分别为47.31/10万与48.28/10万,变化趋势差异无统计学意义(t=0.46,P=0.563)。脑出血死亡率男性高于女性,差异均有统计学意义(均P<0.05)。郊县居民脑出血死亡率高于主城居民,差异有统计学意义(均P<0.05),主城居民脑出血死亡率与标化死亡率分别以年均6.85%与7.41%下降,变化趋势差异均有统计学意义(均P<0.05),郊县居民脑出血死亡率以年均1.90%上升,变化趋势差异有统计学意义(t=3.35,P=0.020)。结论重庆市脑出血发病率、死亡率均低于全国平均水平,但脑出血发病率与死亡率均呈上升趋势,男性与郊县居民是脑出血防治的重点人群。

Objective To understand the trend of the incidence and mortality of intracerebral hemorrhage in Chongqing and to provide the suggestions for intracerebral hemorrhage prevention and control.Methods Cases of the intracerebral hemorrhage(ICD-10:I61-62)were sorted from national reported system of cardiovascular and stroke from 2012 to 2018 in Chongqing.The data were analyzed and calculated indicators including incidence,age standardization incidence rate(ASIR),mortality and age standardization mortality rate(ASMR),proportion of intracerebral hemorrhage by SPSS 25.0.The difference of the incidence and mortality of intracerebral hemorrhage were compared by Chi-square test between male and female,urban and suburb.The trend change of the incidence and mortality of intracerebral hemorrhage were indicated by annual change percent(APC).The trend of APC was tested by t test(α=0.05).Results The incidence and ASIR of intracerebral hemorrhage was 70.87/100000,59.04/100000 in 2012,Chongqing.The incidence and ASIR of intracerebral hemorrhage was 78.15/100000,60.44/100000 in 2018,Chongqing.The incidence and ASIR of intracerebral hemorrhage increased by 4.39%and 3.67%respectively,but the trend change wasn′t significant(P>0.05).The incidence of intracerebral hemorrhage in male was higher than that in female(P<0.05).The incidence of intracerebral hemorrhage in suburb was higher than that in central city(P<0.05).The mortality of intracerebral hemorrhage increased from 58.78/100000 in 2012 to 69.84/100000 in 2018 by 3.77%annually(t=4.38,P=0.007).ASMR of intracerebral hemorrhage was 47.31/100000 in 2012 and 48.28/100000 in 2018 respectively.Trend change of intracerebral hemorrhage wasn′t significant from 2012 to 2018(t=0.46,P=0.563).The mortality of intracerebral hemorrhage in male was higher than that in female(P<0.05).The mortality of intracerebral hemorrhage in suburb was higher than that in central city(P<0.05).The mortality and ASMR of intracerebral hemorrhage in central city decreased by 6.85%and 7.41%significantly(P<0.05).The mortality of intracerebral hemorrhage in suburb increased by 1.90%annually(t=3.35,P=0.020).Conclusion The incidence and mortality of intracerebral hemorrhage in Chongqing was lower than the average level in national wide.The incidence and mortality of intracerebral hemorrhage increased in Chongqing.The male and suburb residents was the crucial population for intracerebral hemorrhage prevention and control.