腹腔镜合并阴式手术治疗原发性阴道腺癌一例

Treatment of Primary Vaginal Adenocarcinoma by the Laparoscopic Surgery Combined with Vaginoplasty:a Case Report

原发性阴道癌临床上罕见,多为另一原发部位肿瘤转移到阴道,常见于绝经后女性。目前阴道癌治疗标准尚未统一,多根据病灶位置、肿瘤分期及病理类型,行个体化治疗,其中以放疗为主。但放疗存在很多远期并发症,如阴道硬化、狭窄等,严重影响年轻患者生活质量。由于高危型人乳头瘤病毒感染的持续存在,原发性阴道癌在年轻女性中发生率有所增加。报告1例年轻原发性阴道腺癌患者的情况,该患者行根治性手术及阴道成形术、术后辅助化疗6个疗程,随访至今未见复发,并复习相关文献,进一步讨论了年轻的阴道癌患者的临床及诊治特点。

Most of vaginal cancer is transferred from other primary site,while primary vaginal cancer is rare in clinical practice.Primary vaginal cancer is often found in postmenopausal women.At present,the treatment standard of vaginal cancer has not been unified,and the individualized treatment is mainly based on the location of the lesion,tumor stage and pathological type.The radiotherapy is the main treatment.However,the radiotherapy has many long-term complications,such as vaginal sclerosis and stenosis,which seriously affect the quality of life of young patients.Due to the persistence of high-risk HPV infection,the incidence of primary vaginal cancer has increased in young women.We reported a case of young patients with primary vaginal adenocarcinoma who underwent radical surgery,vaginoplasty and postoperative adjuvant chemotherapy for 6 courses.Now,the treatment has been completed for 12 months,and there is no recurrence trace.The relevant literature was reviewed,so as to discuss the clinical diagnosis and treatment of young patients with vaginal cancer.