复方生大黄散神阙穴贴敷联合常规医护措施治疗化疗相关性便秘临床研究

An Observation on the Clinical Effect of Application of Compound Shengdahuang Powder at Shenque Point Combined with Conventional Medical Nursing Measures for Tumor Patients with Constipation Caused by Chemotherapy

目的:观察在常规医护措施基础上加用复方生大黄散贴敷神阙穴治疗化疗相关性便秘患者的临床疗效。方法:将116例热积秘患者随机分为对照组和观察组各58例。2组患者均服用麻仁丸,给予常规综合护理措施,观察组加予复方生大黄散贴敷神阙穴,2组疗程均为4周。治疗前、治疗4周后评定便秘主要症状评分、便秘患者症状自评量表(PAC-SYM)评分及便秘患者生活质量自评量表(PAC-QOL)评分,记录患者恢复正常排便的时间。并于治疗4周后由患者自行评价对护理工作的满意度。结果:治疗后,2组粪便性状、排便费力、排便时间等6项症状评分及总分均较治疗前降低(P<0.01),观察组6项症状评分及总分均低于对照组(P<0.01)。2组PAC-SYM腹部症状、直肠症状、大便症状评分及总分均较治疗前降低(P<0.01),观察组3项评分及总分均低于对照组(P<0.01)。2组PAC-QOL生理不适、社会心理不适、担忧、满意度评分及总分均较治疗前降低(P<0.01),观察组4项评分及总分均低于对照组(P<0.01)。观察组恢复正常排便的时间较对照组加快(P<0.01),护理满意度高于对照组(P<0.05)。结论:在常规医护措施的基础上加用复方生大黄散贴敷神阙穴治疗热积型化疗相关性便秘,可显著减轻患者的便秘症状,缩短病程,提高患者的生活质量。

Objective:To observe the clinical effect of application of compound Shengdahuang powder at Shenque point(RN 8) on patients with chemotherapy induced constipation based on conventional medical nursing measures. Methods: A total of 116 patients with heat-accumulation constipation were randomly divided into the control group and the observation group,58 cases in each group. Both groups were given Renma pills and conventional comprehensive nursing measures. The observation group was additionally given compound Shengdahuang powder at Shenque point. Both groups were treated for four weeks. Before treatment and four weeks after treatment,the scores of main symptoms related to constipation,Patient Assessment of Constipation Symptoms(PAC-SYM) and Patient Assessment of Constipation Quality of Life(PAC-QOL) were evaluated,and the time to return to normal defecation was recorded. Four weeks after treatment,the nursing satisfaction was evaluated by patients themselves. Results:After treatment,each score and the total scores of six symptoms in the two groups,including fecal character,laborious defecation and defecation time,were all decreased when compared with those before treatment(P<0.01), and the above scores in the observation group were lower than those in the control group(P<0.01). The scores of abdominal symptoms,rectal symptoms,stool symptoms and the total scores of PAC-SYM in the two groups were all decreased when compared with those before treatment(P<0.01),and the above scores in the observation group were lower than those in the control group(P<0.01). The scores of physical discomfort, psychosocial discomfort,worry,nursing satisfaction and the total scores of PAC-QOL were decreased when compared with those before treatment(P<0.01),and the above scores in the observation group were lower than those in the control group(P<0.01). The time to return to normal defecation in the observation group was faster than that in the control group(P<0.01),and the the score of nursing satisfaction was higher(P<0.05). Conclusion:Based on the conventional medical nursing measures,the additional application of compound Shengdahuang powder at Shenque point to treat chemotherapy-induced heat-accumulation constipation,can significantly reduce the symptoms of constipation,shorten the course of disease,and improve the quality of life of the patients.