摘要
孤独症谱系障碍(autism spectrum disorder,ASD)的病因及发病机制至今尚不明确,临床治疗方法虽多,但疗效不佳且预后较差。在脑肠轴理论的影响下,西医将益生菌作为一种非药物治疗手段,运用于ASD患儿的临床治疗中。中医体系以"脾肾相关""肾通于脑"及"脾为上下枢机"为基础,构建了脾肾-脑相通理论。在此理论的指导下,建立了从肾脾到心脑的治疗原则,一方面可调节肠道菌群平衡,改善局部症状;另一方面,调整患儿全身阴阳平衡,达到临床疗效最大化。
The etiology and pathogenesis of autism spectrum disorder(ASD)are still unclear.Although there are many clinical treatments,the curative effect is unsatisfactory and the prognosis is poor.Under the influence of brain-gut axis theory,probiotics is used as a non-drug treatment in the clinical treatment of children with ASD.On the basis of"spleen kidney correlation","kidney connecting to brain"and"spleen being as upper and lower axis",TCM system has constructed the theory of spleen-kidney-brain communication.Under the guidance of this theory,the treatment principle from kidney and spleen to heart and brain is established.On the one hand,it can adjust the balance of intestinal flora and improve local symptoms;on the other hand,it can adjust the balance of yin and yang in the whole body of children,so as to maximize the clinical efficacy.
作者
张也
郭亚雄
罗世杰
马艳芳
陈艳妮
金瑄
ZHANG Ye;GUO Ya-xiong;LUO Shi-jie;MA Yan-fang;CHEN Yan-ni;JIN Xuan(Shaanxi University of Chinese Medicine,Xianyang,Shaanxi,China,712046;Affiliated Hospital of Shaanxi University of Chinese Medicine,Xianyang,Shaanxi,China,712000)
出处
《河南中医》
2021年第1期20-23,共4页
Henan Traditional Chinese Medicine
基金
陕西省名中医罗世杰工作室项目{陕卫中医发[2018]95号}
陕西省儿科医联体项目(2018B02)
咸阳市科技成果推广计划项目(2019KT-08)
陕西中医药大学中西医结合防治脑发育障碍性疾病创新团队项目{陕中大学科办[2018]1号}。
关键词
孤独症谱系障碍
脾肾-脑相通
脑肠轴
autism spectrum disorder(ASD)
spleen-kidney-brain communication
brain-gut axis
