消癌解毒方治疗晚期肿瘤恶病质临床研究

Clinical Study of Decoction for Removing Cancer and Toxin in the Treatment of Advanced Cancer Cachexia

目的:观察消癌解毒方对晚期肿瘤恶病质患者生活质量的影响。方法:将61例晚期肿瘤恶病质患者按照随机数字表法分为治疗组31例和对照组30例。对照组给予支持治疗和对症处理,治疗组在对照组的基础上口服消癌解毒方治疗。比较两组患者治疗前后卡氏(karnofsky,KPS)评分、临床症状评分及血红蛋白、白蛋白水平。结果:两组患者治疗后KPS评分高于本组治疗前,且治疗组治疗后高于对照组治疗后,差异具有统计学意义(P<0.05)。两组患者治疗后各项临床症状积分低于本组治疗前,且治疗组治疗后纳差、乏力、腹胀评分低于对照组治疗后,差异具有统计学意义(P<0.05)。两组患者治疗后血红蛋白及白蛋白水平高于本组治疗前,且治疗组治疗后高于对照组治疗后,差异具有统计学意义(P<0.05)。结论:消癌解毒方治疗晚期肿瘤恶病质,能明显减轻患者临床症状,提高生活质量。

Objective:To observe the effect of Decoction for Removing Cancer and Toxin on the quality of life of patients with advanced cancer cachexia.Methods:A total of 61 patients with advanced cancer cachexia were randomly divided into the treatment group with 31 cases and the control group with 30 cases.The control group was given supportive treatment and symptomatic treatment,while the treatment group was additionally given Decoction for Removing Cancer and Toxin on the basis of the control group.Karnofsky(KPS)score,clinical symptom score,hemoglobin and albumin levels were compared between the two groups before and after the treatment.Results:KPS score of the two groups after the treatment was higher than that of the same group before the treatment,and the KPS score of the treatment group was higher than that of the control group,the difference was statistically significant(P<0.05).The clinical symptom score of the two groups after treatment was lower than that of the same group before treatment,and the clinical symptom score of the treatment group was lower than that of the control group,and the difference was statistically significant(P<0.05).Hemoglobin and albumin levels of the two groups after treatment were higher than those of the same group before the treatment,and the above two levels of the treatment group were higher than those of the control group,and all the differences were statistically significant(P<0.05).Conclusion:In terms of advanced cancer cachexia,Decoction for Removing Cancer and Toxin can significantly reduce the clinical symptoms and improve the quality of life of the patients.