高分辨磁共振血管壁成像对腔隙性脑梗人群豆纹动脉血管形态特征分析

Analysis of the vascular morphological characteristics of lenticular artery in population with lacunar cerebral infarction by HR-MRI VWI

目的:采用高分辨率磁共振血管壁成像(HR-MRIVWI)技术,探讨腔隙性脑梗人群中豆纹动脉(LSA)数量及深度。方法:选取在医院就诊的30例腔隙性脑梗死患者,将其纳入腔隙性脑梗死组;另选取25名健康志愿者纳入对照组。对所有受试者进行HR-MRIVWI技术中T1加权成像的三维体积各向同性涡轮自旋回波采集(T_1WI-3DVISITA)序列,使用后处理应用Philips Intellispace portal软件对图像进行处理,以最小密度投影法(MinIP)重建血管图像进行分析,观察LSA分支的数量及深度,并使用SPSS21.0软件进行统计分析。结果:两组左侧、右侧的LSA分支深度比较,差异均有统计学意义(t=4.225,t=3.242;P<0.05);两组左侧、右侧LSA的数目比较,差异有统计学意义(t=10.238,t=14.308;P<0.05)。结论:腔隙性脑梗塞患者的双侧LSA的数量及深度低于正常人群,HR-MRIVWI对LSA形态学特征分析具有一定的临床价值。

Objective:To explore the number and depth of lenticular arteries in population with lacunar cerebral infarction by adopting high-resolution magnetic resonance vascular wall imaging(HR-MRI VWI)technique.Methods:30 patients with lacunar cerebral infarction in the hospital were selected and were included in the lacunar cerebral infarction group,and another 25 healthy volunteers were divided into the control group.And all of patients underwent the T1WI-3D VISITA sequence of HR-MRI VWI technique,and the image was processed by the post-processing application software Philips Intelligent portal software.The minimum intensity projection(MinIP)method was used to reconstruct the blood vessel image for analysis,and the number and depth of the branch of lenticular artery were further observed,and SPSS 21.0 software was used to implement statistical analysis.Results:The differences of the depth of the branch of lenticular arteries of left side and right side between two groups were significant(t=4.225,t=3.242,P<0.05).And the number of lenticular arteries of left side and right side between the two groups were significant(t=10.238,t=14.308,P<0.05).Conclusion:The number and depth of bilateral lenticular arteries in patients with lacunar cerebral infarction are lower than those in normal population.HR-MRI VWI technique has a certain of clinical value for the analysis of morphological characteristics of lenticular artery.