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伴单克隆IgG沉积的增生性肾小球肾炎1例

A case of proliferative glomerulonephritis with monoclonal IgG deposits
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摘要 单克隆免疫球蛋白病(monoclonal gammopathy,MGP)相关增生性肾小球肾炎是由异常单克隆增殖的B淋巴细胞或浆细胞持续分泌的免疫球蛋白,通过直接和间接机制导致的增生性肾小球肾炎。直接机制为:单克隆免疫复合物沉积于肾小球系膜区和毛细血管袢,并且激活补体经典途径,最终形成单克隆免疫球蛋白及补体在肾脏的沉积,导致的肾小球膜增生样病。
作者 王淑伟 朱立革 刘国平 Wang Shuwei;Zhu Lige;Liu Guoping
出处 《中华肾病研究电子杂志》 2020年第6期285-287,共3页 Chinese Journal of Kidney Disease Investigation(Electronic Edition)
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