中国新生儿领域临床实践指南的质量评价

Quality assessment of clinical practice guidelines in neonatal field in China

目的对中国新生儿领域相关指南进行质量评价,为今后循证指南的研发与制订提供参考。方法计算机检索CBM、VIP、WanFang Data、CNKI和医脉通数据库,搜集中国新生儿领域相关的临床实践指南,检索时限均从2000年1月1日至2020年6月28日。4名研究者独立筛选文献、提取资料,使用AGREEⅡ评价纳入指南的方法学质量,使用RIGHT评价纳入指南的报告质量,并报告各领域条目评分和报告率。结果共纳入指南35部,发表数量基本呈逐年上升趋势。使用AGREEⅡ评分结果显示,2017年后发表指南在各领域评分均高于2017年前,其中评分最高为清晰性领域(82.9%),最低为编辑独立性领域(15.4%)。使用RIGHT评分结果显示,2017年后发表的指南在绝大部分领域报告率高于2017年前。报告比例最高的领域均为基本信息(75.6%vs.65.0%),2017年前发表指南报告最低的领域为评审和质量保证(0%),而2017年后为其他方面(4.4%)。结论中国新生儿领域指南发展迅速,但指南质量仍需不断改进。

Objective To evaluate the quality of Chinese guidelines of newborns so as to provide references for the formulation of relevant guidelines for newborns in the future.Methods CBM,VIP,WanFang Data,CNKI and Medlive databases were systematically searched to collect clinical practice guidelines in neonatal field in China from January 1st,2000 to June 28th,2020.Four researchers independently screened literature,extracted data,used AGREEⅡto evaluate the methodological quality of the guidelines,used RIGHT to evaluate the reporting quality of the guidelines,and analyzed the score and reporting rate of items in each field.Results A total of 35 guidelines were included,and the quantity of publications increased annually.The AGREEⅡscore showed that guidelines published after 2017 were rated higher in all areas than that prior to 2017,with clarity scoring highest(82.9%)and editorial independence scoring lowest(15.4%).The RIGHT score showed that guidelines published after 2017 had higher reporting rates in most areas than that prior to 2017.The highest proportion of reported areas was basic information(75.6%vs.65.0%).Areas with the lowest reporting ratios in the guidelines prior to 2017 were review and quality assurance(0%),while after 2017 were other areas(4.4%).Conclusions Neonatal guidelines in China have developed rapidly and the quality of the guideline still requires improvement.