妊娠期糖尿病患者血清空腹血糖、餐后2h血糖、糖化血红蛋白水平变化及其与不良妊娠结局的关系研究

Changes of serum fasting blood glucose,postprandial 2h blood glucose and glycosylated hemoglobin in patients with gestational diabetes mellitus and their relationship with adverse pregnancy outcomes

目的分析妊娠期糖尿病患者血清空腹血糖、餐后2h血糖、糖化血红蛋白水平变化及其与不良妊娠结局之间的关系。方法本次研究选择2018年1月至2019年1月到本院完成治疗的74例妊娠期糖尿病患者作为研究组,另外选择同一时间段参加检查的健康产妇74例作为参照组,共148例。观察两组患者的血清各项指标以及不良妊娠出现情况,并对数据作出简要对比分析。结果研究组患者的血清PBG、FBG、HbAlc水平较参照组而言都出现了明显的升高,且不良妊娠情况较多,血清PBG、FBG、HbAlc水平与不良妊娠之间呈现出正相关的关系,本次对比数据对比差异明显(P<0.05)。结论妊娠期糖尿病患者的PBG、FBG、HbAlc水平将会有明显的升高,这种情况还会诱发不同类型的不良妊娠结局,在母婴的健康成长中是一项重大的危险因素。

Objective:To analyze the changes of serum fasting blood glucose,postprandial blood glucose,glycosylated hemoglobin and their relationship with adverse pregnancy outcomes in patients with gestational diabetes mellitus.Methods:In this study,74 patients with gestational diabetes mellitus who completed treatment in our hospital from January 2018 to January 2019 were selected as the study group,and 74 healthy parturients who participated in the examination at the same time were selected as the reference group,with a total of 148 cases.To observe the serum indicators and the occurrence of adverse pregnancy in the two groups,and make a brief comparative analysis of the data.Results:Compared with the reference group,the levels of PBG,FBG and HbAlc in serum of patients in the study group increased significantly,and there were more adverse pregnancies.There was a positive correlation between the levels of PBG,FBG and HbAlc in serum and adverse pregnancies,and there was a significant difference in this comparison data(P<0.05).Conclusion:The levels of PBG,FBG and HbAlc in gestational diabetes mellitus patients will increase obviously,and this situation will also induce.