醒脑静治疗中风中脏腑的临床疗效观察

Clinical observation of Xingnaojing in treating the viscera of stroke

目的探析中风中脏腑患者应用醒脑静治疗的临床效果。方法将我院48例2015年1月~2018年12月收治的中风中脏腑患者根据辨证分型分成两组,甲组(痰火瘀闭证,n=24)和乙组(痰浊瘀闭证,n=24),两组患者均给予醒脑静注射液静脉滴注治疗,比较分析两组临床疗效、治疗前后主要症状评分、神经功能缺损程度评分。结果甲组总有效率为95.83%,明显比乙组(75.00%)高,差异有统计学意义(P <0.05)。两组治疗后神识欠清、牙关紧闭、口噤不开、肢体强痉症状评分与治疗前比较,差异有统计学意义(P <0.05),且甲组各症状评分均显著低于乙组,差异有统计学意义(P <0.05)。两组治疗后神经功能缺损程度评分明显低于治疗前,差异有统计学意义(P <0.05),且甲组评分显著低于乙组,差异有统计学意义(P <0.05)。结论中风中脏腑患者应用醒脑静注射液治疗的临床效果十分确切,尤其是对于痰火瘀闭证患者来说,能够进一步缓解患者临床症状,减轻患者神经功能缺损程度,值得临床深入研究与推广应用。

Objective To investigate the clinical effect of Xingnaojing in the treatment of patients with apoplexy involving the viscera. Methods A total of 48 patients with apoplexy involving the viscera admitted to and treated in our hospital from January 2015 to December 2018 were divided into two groups according to syndrome differentiation, namely Group A(syndrome of blockade caused by phlegm-fire stasis and blockade, n=24) and Group B(syndrome of blockade of phlegm-turbidity and static blood, n=24). The patients in both groups were treated with Xingnaojing injection by intravenous infusion. The clinical efficacy, main symptoms scores, and neurological deficit scores before and after treatment were compared and analyzed between the two groups. Results The total effective rate was 95.83% in Group A, which was significantly higher than that in Group B(75.00%), with a statistically significant difference(P < 0.05). Compared with the symptom scores before treatment, there were statistically significant differences in the symptom scores of unconsciousness, trismus, lockjaw, and strong limb spasms between the two groups after treatment(P < 0.05), and the symptom scores in Group A were significantly lower than those in Group B, with statistically significant differences(P < 0.05). The neurological deficit scores after treatment in the two groups were significantly lower than those before treatment, with statistically significant differences(P < 0.05), and the scores in Group A were significantly lower than those in Group B, with statistically significant differences(P < 0.05). Conclusion Xingnaojing injection has a definite clinical effect for patients with apoplexy involving the viscera, especially for patients with syndrome of blockade caused by phlegm-fire stasis and blockade. The drug can further relieve the clinical symptoms of patients and reduce the degree of neurological deficits, and is worthy of in-depth clinical research, promotion and application.