经鼻持续气道正压通气治疗新生儿肺炎的临床疗效观察

Clinical Observation of Nasal Continuous Positive Airway Pressure in the Treatment of Neonatal Pneumonia

目的分析经鼻持续气道正压通气治疗新生儿肺炎的临床应用效果。方法选取惠阳三和医院2018年1月至2019年1月收治的70例新生儿肺炎患儿作为研究对象,采用随机数字表法分为观察组(35例)与对照组(35例)。对照组使用常规鼻导管治疗,观察组则使用经鼻持续气道正压通气进行干预。比较两组患儿临床症状消失时间和住院时间,以及治疗前后的血气指标、心率、呼吸频率及新生儿危重病例(NCIS)评分。结果治疗前,两组患儿的二氧化碳分压(PaCO2)、氧分压(PaO2)和血氧饱和度(SaO2)心率、呼吸频率、NCIS评分比较,差异无统计学意义(P>0.05)。治疗后,两组患儿的各项指标明显改善,且观察组患儿的各项指标均显著优于对照组(P<0.05)。观察组患儿呼吸困难、肺部湿啰音消失时间、血气指标恢复正常时间和住院时间均短于对照组(P<0.05)。观察组患儿治疗总有效率显著高于对照组(P<0.05)。结论选择经鼻持续气道正压通气治疗新生儿肺炎的临床效果显著优于传统治疗方式,可促使疾病的早期转归和改善,进一步提高治疗总有效率。

Objective To analyze the clinical effect of nasal continuous positive airway pressure(NAPP)in the treatment of neonatal pneumonia.Methods Totally 70 children with neonatal pneumonia admitted to Huiyang Sanhe Hospital from January 2018 to January 2019 were selected,and divided into observation group and control group by random number table method,with 35 cases in each group.The control group was treated with conventional nasal catheter,while the observation group was treated with nasal continuous positive airway pressure.The time of disappearance of clinical symptoms and length of hospital stay,as well as blood gas index,heart rate,respiratory rate and NCIS score before and after treatment were compared between the two groups.Results Before treatment,there were no significant differences in PaCO2,PaO2,SaO2,heart rate,respiratory rate and NCIS scores between the two groups(P>0.05).After treatment,the indicators of children in both groups were significantly improved,and the indicators of children in the observation group were significantly better than those in the control group(P<0.05).The dyspnea,disappearance time of pulmonary moist rales,recovery time of blood gas index and hospitalization time in the observation group were shorter than those in the control group(P<0.05).The total effective rate in the observation group was significantly higher than that in the control group(P<0.05).Conclusion The effect of nasal continuous positive airway pressure in the treatment of neonatal pneumonia is significantly better than that of traditional treatment,which promotes the early prognosis and improvement of the disease,and further improve the total effective rate of treatment.