冠状动脉微血管功能障碍临床诊疗研究新进展

New Progress in Clinical Diagnosis and Treatment of Coronary Microvascular Dysfunction

冠状动脉微血管功能障碍(Coronary Microvascular Dysfunction,CMD)是冠心病的一种特殊类型。冠状动脉微血管的功能或者结构异常会导致患者由于心肌缺血、缺氧引起心脏病,相关疾病涉及微血管心绞痛、心脏X综合征、冠脉慢血流现象等。患者临床症状以反复发作的心绞痛较为多见,随后可进展成急性冠脉综合征、缺血性心肌病或者心源性猝死等,若能够尽早提供合理有效的诊疗方式,可快速稳定患者病情,保障预后,提升生存质量。由此本文展开综述,探讨CMD的发病机制、临床特点以及可能的诊断和治疗策略,为后续临床诊治提供一定指导意义。

Coronary Microvascular Dysfunction(CMD)is a special type of coronary heart disease.It is because the abnormal function or structure of coronary microvessels leads to heart disease caused by myocardial ischemia and hypoxia.The related diseases involve microvascular angina,cardiac X syndrome,coronary slow blood flow phenomenon,etc.The clinical symptoms of patients are more common with recurrent angina pectoris,which can then develop into acute coronary syndrome,ischemic cardiomyopathy or sudden cardiac death,etc.If reasonable and effective diagnosis and treatment can be provided as soon as possible,the patients'condition can be stabilized rapidly,the prognosis can be guaranteed,and the quality of life can be improved.In this paper,the pathogenesis,clinical characteristics,possible diagnosis and treatment strategies of CMD were discussed to provide some guidance for subsequent clinical diagnosis and treatment.