角膜移植术后干眼的研究进展

Research progress of dry eye after corneal transplantation

由于角膜移植手术对眼表结构的破坏和长期滴眼液的应用,使得干眼成为较为常见的移植术后并发症,长期干眼会导致角膜上皮缺损,影响植片的存活。为提高对于角膜移植术后干眼的认识,本文通过查阅国内外相关文献,对于角膜移植术后干眼的发病机制、临床表现、治疗和预防进行综述,为临床应用提供参考。

Dry eye has become one of the relatively common complications following keratoplasty due to the surgical destruction of the ocular surface and long-term application of topical eye drops.Dry eye will result in corneal epithelial defects and further could decrease the survival rate of the grafts.In order to better understand dry eye following corneal transplantation and to provide clinical guidance for physicians,we reviewed recent domestic and international published literatures regarding its pathogenesis,clinical features,prevention and management.