地佐辛在老年骨科术后镇痛的疗效与安全性评价

Evaluation of the efficacy and safety of dezocine in postoperative analgesia of elderly orthopaedic

目的:研究分析地佐辛在老年骨科术后镇痛的效果与安全性。方法:选取2017年1月-2020年1月行手术治疗的老年骨科患者1400例,根据术后镇痛方式不同分为两组,各700例。甲组采用舒芬太尼镇痛,乙组采用地佐辛镇痛,比较两组术后镇痛效果和不良反应发生率。结果:两组术后2 h、4 h和8 h疼痛视觉模式评分法(VAS)比较,差异无统计学意义(P>0.05);乙组不良反应发生率低于甲组,差异有统计学意义(P<0.05)。结论:在老年骨科患者的术后镇痛中,应用地佐辛镇痛效果显著,且不良反应发生率低,安全性更高,若老年骨科患者无特殊需求,可将地佐辛作为术后镇痛的首选方案。

Objective:To study and analyze the analgesic effect and safety of dezocine in elderly patients after orthopaedic surgery.Methods:From January 2017 to January 2020,1,400 elderly orthopaedic patients who underwent surgery were selected and divided into two groups according to different postoperative analgesia methods,with 700 patients in each group.Group A was treated with sufentanil for analgesia.Group B was treated with dezocine for analgesia.The incidence of postoperative analgesia and adverse reactions were compared between the two groups.Results:VAS scores at 2 h,4 h and 8 h after surgery were compared between the two groups,the difference was not statistically significant(P>0.05).The incidence of adverse reactions in group B was lower than the group A,the difference was statistically significant(P<0.05).Conclusion:Postoperative analgesia in elderly orthopaedic patients,the analgesic effect of applying dezocine is remarkable,and with a low incidence of adverse reactions and higher safety,if elderly orthopaedic patients have no special needs,dezocine may be the first choice for postoperative analgesia.