超声微泡与辐射防护的相关研究进展

Research progress on ultrasound microbubbles and radiation protection

放射治疗是一种重要的医疗手段,其产生的电离辐射在发挥治疗效果的同时,也会对局部机体或全身造成不同程度的损伤。现有的辐射防护剂因价格高昂、具有副作用等因素应用受到限制。近年来,超声微泡作为药物等治疗性物质的理想载体,其载药特性及通过超声辐照爆破靶向药物传递的特性在生物医学领域有极大的应用潜力。本文就有望载入超声微泡进行抗辐射作用的药物和材料进行综述,为研发理想的新型抗辐射药物及方式提供参考。

Radiotherapy is an important medical method.The ionizing radiation from radiotherapy not only plays a therapeutic effect,but also causes different degrees of damage to the local body or the whole body.Current radiation protection agents are limited in application due to the unaffordable price and serious side effects.In recent years,As an ideal carrier of drugs and other therapeutic substances,ultrasonic microbubbles have great application potential in the field of biomedicine because of their drug-carrying characteristics and targeting drug delivery through ultrasonic irradiation blasting.In this paper,the drugs and materials that can be loaded into ultrasound microbubbles for anti-radiation effects are reviewed,which will provide reference for the research and development of ideal new radiation resistance drugs and methods.