探究普外科术后患者行肠外营养支持的临床疗效

Clinical effect of parenteral nutrition for patients after general surgery

目的探究普外科术后患者行肠外营养支持(PN)的临床疗效。方法100例行普外科手术治疗的患者,随机分为试验组和对照组,各50例。对照组术后给予肠内营养支持治疗,观察组患者术后给予肠外营养支持治疗。对比两组视黄醇结合蛋白、前白蛋白和白蛋白水平,胃排空恢复时间、肠道排气时间及住院时间,术后并发症发生情况,空腹血糖水平。结果观察组视黄醇结合蛋白及前白蛋白水平分别为(37.40±4.87)mg/L、(289.47±49.82)g/L,均高于对照组的(23.51±4.56)mg/L、(226.66±46.23)g/L,差异有统计学意义(P<0.05)。观察组胃排空恢复时间、肠道排气时间及住院时间均短于对照组,差异有统计学意义(P<0.05)。观察组术后并发症发生率4.00%显著低于对照组的16.00%,差异有统计学意义(P<0.05)。对照组术后第7天空腹血糖水平高于术后第1天和观察组术后第7天,差异有统计学意义(P<0.05)。结论针对普外科术后患者采取肠外营养支持干预效果好,操作简单,安全可靠,可加速肠功能恢复,减少并发症,临床应用价值高。

Objective To investigate the clinical efficacy of parenteral nutrition(PN)for patients after general surgery.Methods A total of 100 patients undergoing general surgery were randomly divided into experimental group and control group,with 50 cases in each group.The control group was treated with enteral nutrition after operation,and the observation group was treated with parenteral nutrition after operation.The retinol binding protein,prealbumin and albumin,gastric emptying recovery time,intestinal exhaust time and total hospitalization time,incidence of postoperative complications,and fasting blood glucose levels were compared between the two groups.Results The retinol binding protein and prealbumin of the observation group were(37.40±4.87)mg/L and(289.47±49.82)g/L,which were all higher than(23.51±4.56)mg/L and(226.66±46.23)g/L of the control group,and the difference was statistically significant(P<0.05).The gastric emptying recovery time,intestinal exhaust time and total hospitalization time of the observation group were shorter than those of the control group,and the difference was statistically significant(P<0.05).The incidence of postoperative complications 4.00%of the observation group was significantly lower than 16.00%of the control group,and the difference was statistically significant(P<0.05).7 day after operation,the fasting blood glucose of the control group was higher than that 1 day after operation and the observation group 7 day after operation,and the difference was statistically significant(P<0.05).Conclusion Parenteral nutrition support intervention has good results for patients after general surgery,which can accelerate the recovery of intestinal function,reduce complications with simple operation.It is safe and reliable,and has high clinical application value.