摘要
Biodegradable orthopedic materials(BOMs)are used in rehabilitation and reconstruction of fractured tissues.The response of BOMs to the combined action of physiological stress and corrosion is an important issue in vivo since stress-assisted degradation and cracking are common.Although the degradation behavior and kinetics of BOMs have been investigated under static conditions,stress effects can be very serious and even fatal in the dynamic physiological environment.Since stress is unavoidable in biomedical applications of BOMs,recent work has focused on the evaluation and prediction of the properties of BOMs under stress in corrosive media.This article reviews recent progress in this important area focusing on biodegradable metals,polymers,and ceramics.
基金
This work was jointly supported by the National Natural Science Foundation of China(Grant No.31570961)
Scientific Research Foundation of Graduate School of Southeast University(YBJJ1525)
Hong Kong Research Grants Council(RGC)General Research Funds(GRF)No.11301215.