摘要
To improve the osteointegration property of biomedical titanium,nano-architectured electroactive coating was synthesized through the electrochemical polymerization of dopamine and pyrrole.The highly binding affinity of Ca2t to the catechol moiety of doped dopamine enabled efficient interaction between polypyrrole/polydopamine nanowires and mineral ions.The results indicate that the PPy/PDA nanowires preserved its efficient electro-activity and accelerated the hydroxyapatite deposition in a simulated body fluid.The PPy/PDA nanowires coating could be applied to promote the osteointegration of titanium implant.
基金
oundation of China(grant numbers 51372087,51541201)
the National High Technology Research and Development Program of China(863 Program)(grant number 2015AA033502)
the Science and technology program of Guangzhou(grant number 201707010200)
the Natural Science Foundation of Guangdong Province(grant number 2016A030308014).