继发性草酸盐肾病并急性肾损伤1例报道

Secondary oxalate nephropathy with acute renal injury:A case report

草酸盐肾病是指原发性或者继发性因素引起的高草酸尿症导致草酸钙结晶在肾小管内沉积,继而造成肾脏损害,持续的草酸钙结晶沉着可引起肾脏纤维化,最终会导致终末期肾病的一种代谢性疾病。草酸盐肾病较为罕见,由于临床上未予重视,以及未能行肾活检明确诊断,导致对此疾病认识不足,容易误诊或者漏诊,而早期及时的治疗可以有效延缓肾功能恶化。本文通过对我科收治的1例继发性草酸盐肾病患者进行分析并复习相关文献,讨论该疾病的病因、诊断、治疗及预后等内容,以提高对此疾病的认识。

Oxalate nephropathy is a metabolic renal disease caused by primary or secondary factors of hyperoxaluria,which results in the deposition of calcium oxalate crystals in renal tubules and then causes renal damage.Continuous calcium oxalate crystallization can cause renal fibrosis and eventually lead to end-stage renal disease.Oxalate nephropathy is relatively rare.Due to the lack of clinical attention and the failure to make a definite diagnosis by renal biopsy,we lack sufficient understanding of this disease and are prone to misdiagnosis or missed diagnosis.However,early and timely treatment can effectively delay the deterioration of renal function.In this paper,a patient with secondary oxalate nephropathy admitted to our department was analyzed,and the relevant literature was reviewed to discuss the etiology,diagnosis,treatment,and prognosis of the disease,so as to improve the understanding of this disease.