血栓弹力图在急性轻中度脑梗死患者中的临床应用

Clinical application of Thromboelastography in patients with acute mild to moderate cerebral infarction

目的:探讨血栓弹力图在急性轻中度脑梗死患者中的临床应用。方法:回顾性分析我院神经内科2017年10月〜2019年10月收治的268例轻中度脑梗死患者,患者入院经过评分,分为轻度脑梗死152例和中度脑梗死116例,分别设为轻度组和中度组。检测各组血栓弹力图(TEG)的5项主要指标:凝血反应时间R(min)、凝血形成时间K(min)、a角(°)、最大振幅MA(mm)和凝血系数CI;以及每组治疗前后5项指标的变化。结果:急性脑梗死轻度和中度患者的TEG5项指标均有明显差异,具有统计学意义(P<0.05),急性脑梗死轻度组和中度组治疗前后的TEG5个指数变化明显,具有统计学意义(P<0.05)。结论:利用血栓弹力图可以预测和评估急性轻中度脑梗死,具有一定的临床推广价值。

Objective:To explore the clinical application of thromboelastography in patients with acute mild to moderate cerebral infarction.Methods:A retrospective analysis of 268 patients with mild to moderate cerebral infarction in the Department of Neurology of our hospital from October 2017 to October 2019 was conducted.All patients were admitted within 48 hours after onset.The patients were divided into mild cerebral infarction group(n=152)and moderate cerebral infarction group(n=116).The five main indexes of thromboelastogram(TEG)in each group were detected:coagulation reaction time(R),coagulation formation time(K),a angle,maximum amplitude(MA)and coagulation coefficient(CI),as well as the changes of 5 indexes in each group before and after treatment.Results:There were significant differences in TEG5 indexes between mild and moderate acute cerebral infarction patients,and there were significant changes in TEG5 indexes before and after treatment in mild and moderate acute cerebral infarction groups.Conclusion:Thromboelastogram can be used to predict and evaluate acute mild to moderate cerebral infarction,which has a certain clinical value.