摘要
目的:观察中医温阳法联合恩替卡韦治疗乙肝肝硬化的临床疗效。方法:选择符合诊断标准的患者98例,随机分为两组各49例。对照组予常规保肝治疗+抗病毒治疗(恩替卡韦),治疗组在对照组基础上予口服中药温阳调肝方。两组均治疗24周。比较两组治疗后的临床疗效、治疗前后的肝功能指标(ALT、AST、TBIL、ALB)、肝脏瞬时弹性值(LSM)。结果:治疗组临床治疗总有效率91.8%高于对照组的75.5%(P﹤0.05);治疗后,治疗组LSM值及肝功能(AST、ALT、TBIL、ALB)水平均低于对照组(P﹤0.05)。结论:温阳法联合恩替卡韦治疗乙肝肝硬化代偿期的效果显著,可显著改善肝功能,降低肝脏硬度(LSM)。
Objective:To observe the clinical effect of warming yang therapy of TCM and entecavir on hepatitis B cirrhosis.Methods:98 cases of selected patients who met the inclusion criteria were randomly divided into two groups,49 cases in each group.The control group was treated by conventional liver-conserving therapy and antiviral therapy(entecavir),while the treatment group was treated with warming yang and adjusting liver recipe(oral Chinese herbal medicine)on the basis of control group.Both groups were treated for 24 weeks.The clinical effect after treatment and the liver function indexes(ALT,AST,TBIL,ALB)and liver stiffness measurement value(LSM)before and after treatment were compared between two groups.Results:The clinical total effective rate of treatment group was 91.8%,which was higher than 75.5%of control group(P﹤0.05).After treatment,LSM value and liver function level(AST,ALT,TBIL,ALB)of treatment group were lower than those of control group(P﹤0.05).Conclusion:The clinical effect of warming yang therapy and entecavir on decompensated hepatitis B cirrhosis is significant,which can improve the liver function significantly,and reduce the liver stiffness measurement value(LSM).
作者
王德运
李慧
赵学印
WANG De-yun;LI Hui;ZHAO Xue-yin(Taian Hospital of Traditional Chinese Medicine,Shandong Province,Taian271000,China;不详)
出处
《山西中医》
2021年第2期22-23,26,共3页
Shanxi Journal of Traditional Chinese Medicine
基金
山东省中医药科技发展计划项目(编号:2019-0758)。
关键词
乙肝肝硬化
温阳法
恩替卡韦
中西医结合疗法
hepatitis B cirrhosis
warming yang therapy
entecavir
integrated therapy of traditional Chinese and western medicine