Growth retrieval of stressed bacterial cells: logic and contradictions

Study of bacterial stress response against an array of stress signals like heat shock and oxidative stress has been well accomplished so far.Several stress factors cause microorganisms to go under the viable but nonculturable state.However,the growth resuscitation of bacterial cells from such viable but nonculturable state is still obscure.Current review briefly focused on the growth revival of the viable but nonculturable cells and placed the possible model of growth resuscitation.The significance of such type of study on the viable but nonculturable cells principally relies upon clinical sectors whereby some pathogens are found to be latent for many days and thereby imparting the false negative results as well as in the food industries whereby the viable but nonculturable cells may cause massive damage in the public health upon their resuscitation.