季铵盐类聚合物增强纳米抗菌材料性能的研究进展

Reserch Progress of Properties Enhanced by Quaternary Ammonium Salt Polymers of Nano-Antibacterial Materials

季铵盐类聚合物由于具有正电荷,可以通过静电作用吸附于细菌细胞膜,破坏细菌细胞膜结构,因而在抗菌方面具有独特应用。近年来,将季铵盐类聚合物与纳米抗菌材料结合以提高材料的抗菌性能取得一系列的研究成果。该文综述了近年来季铵盐类聚合物修饰无机纳米抗菌材料后在增强材料分散性、稳定性、抗菌活性以及降低毒性方面的研究进展,举例说明了常见的季铵盐类聚合物修饰前后对无机纳米材料抗菌活性的影响,并分析了作用机理。最后,对季铵盐类聚合物增强纳米抗菌材料性能的应用及未来发展方向进行了展望。

Due to the positive charge,quaternary ammonium salt polymer can be adsorbed onto the bacterial cell membrane by electrostatic action,destroying the structure of the bacterial cell membrane,which has a unique application in antibacterial field.In recent years,a series of research have been carried out in the combination of quaternary ammonium salt polymers and nano antibacterial materials to improve the antibacterial properties of the materials.This review focuses on recent research progress in enhancing dispersion,stability,antibacterial activity and reducing toxicity of inorganic nano-antibacterial materials modified by quaternary ammonium salt polymers.Examples were given to illustrate the effects of common quaternary ammonium salts on the antibacterial activity of nanomaterials,and analyze the enhancement mechanism.Finally,the applications of quaternary ammonium salt polymers to enhance the properties of nano-antibacterial materials in the future were prospected.