妊娠期血脂水平与小于胎龄儿相关性研究进展

Association between maternal blood lipid level during pregnancy and risk of small-for-gestational-age infants

小于胎龄儿(SGA)是常见不良妊娠结局之一,也是新生儿围产期死亡及成年后罹患代谢性疾病的危险因素,加强早期监测与干预对预防SGA具有重要意义。妊娠期血脂异常作为一种常见的妊娠期代谢紊乱,可能与SGA发生风险增加有关,但目前相关的流行病学研究结果并不一致。本文对近年来国内外妊娠期血脂水平与SGA相关性研究作一综述,为SGA预防及干预提供参考。

Small for gestational age(SGA),one of the major adverse pregnancy outcomes,significantly increases the risk of perinatal death and metabolic diseases in adulthood.It is of great significance to strengthen early surveillance and intervention for SGA prevention.Dyslipidemia during pregnancy,as a common metabolic disorder,has been considered to correlate with the increased risk of SGA;however,the epidemiological evidence is still controversial.We have systematically reviewed the recent studies related to the association between serum lipid level during pregnancy and the risk of SGA,so as to provide reference for prevention and intervention of SGA.