自拟柴胡益神方联合艾司唑仑片改善心脾两虚型失眠患者睡眠障碍的临床研究

Clinical Study on the Improvement of Sleep Disorders in Patients with Insomnia with Deficiency of Self-made Heart and Spleen by Chaihu Yishen Recipe Combined with Estazolam Tablets

目的:观察失眠患者采用自拟柴胡益神方联合艾司唑仑的治疗效果。方法:纳入2018年1月~2019年1月我院接诊的107例失眠患者作为观察对象,掷币法分组,对照组53例予以传统西药治疗,观察组54例加用中药自拟柴胡益神方治疗,采用匹兹堡睡眠治疗指数(PSQI)评价患者睡眠状况,采用睡眠严重程度指数(ISI)评价睡眠严重程度,比较两组患者效果及PSQI评分及ISI评分。结果:观察组PSQI评分显著低于对照组,差异显著(P<0.05);观察组中医证候积分及ISI评分均低于对照组,总有效率(94.44%)高于对照组(71.70%),差异显著(P<0.05)。结论:自拟柴胡益神方能通过中医清热化痰、健脾利水、养心安神等功效,从而降低PSQI评分、ISI评分级中医症候积分,改善患者睡眠质量,提高患者生活质量,治疗效果显著,值得推荐。

Objective:To observe the therapeutic effect of self-made Chaihu Yishen Recipe combined with estazolam in patients with insomnia.Methods:A total of 107 insomnia patients admitted to our hospital from January 2018 to January 2019 were enrolled in the study.The coin-injection method was divided into groups.53 patients in the control group were treated with traditional western medicine.54 patients in the observation group were treated with Chinese medicine.Shenfang treatment,the Pittsburgh Sleep Therapy Index(PSQI)was used to evaluate the patient’s sleep status,and the sleep severity index(ISI)was used to evaluate the severity of sleep.The effect of the two groups and the PSQI score and ISI score were compared.Results:The PSQI score of the observation group was significantly lower than that of the control group(P<0.05).The TCM syndrome score and ISI score of the observation group were lower than the control group,and the total effective rate(94.44%)was higher than that of the control group(71.70%).The difference was significant(P<0.05).Conclusion:Selfmade Chaihu Yishen can reduce the PSQI score,ISI score,TCM symptom scores,improve the patient’s sleep quality,improve the patient’s quality of life,and improve the treatment effect through the functions of clearing heat and removing phlegm,strengthening the spleen and diminishing water,nourishing the heart and calming the nerves.,Recommended.