人工肝血浆置换治疗仪用于乙型重症肝炎治疗的临床疗效

Clinical Effect of Artificial Liver Plasmapheresis in the Treatment of Severe Hepatitis B

目的:探讨人工肝血浆置换治疗仪用于乙型重症肝炎治疗的临床疗效。方法:选择2016年1月~2018年7月在本院接受治疗的80例乙型重症肝炎患者作为本次的研究对象,患者入院后随机分为观察组与对照组,每组40例,对照组患者均给予综合治疗。观察组患者在此基础上给予人工肝血浆置换仪实施血浆置换治疗,比较两组患者治疗前后的生化指标改变,并比较两组患者的治疗有效率。结果:治疗前,两组患者的ALT、AST、ALB、PTA、TBIL差异无统计学意义,P>0.05,具有可比性。治疗后,观察患者的各项生化指标改善均明显优于对照组,P<0.05,有统计学意义。观察组总有效率为85.0%(34/40),明显高于对照组的65.0%(26/40),P<0.05,有统计学意义。结论:对乙型重症肝炎患者采用人工肝血浆置换治疗仪治疗,能有效改善患者的肝功能,疗效确切。

Objective:To investigate the clinical effect of artificial liver plasmapheresis in the treatment of severe hepatitis b.Method:80 patients with severe hepatitis b who were treated in our hospital from January 2016 to July 2018 were selected as the subjects of this study.After admission,the patients were randomly divided into observation group and control group,with 40 cases in each group.Patients in the control group were given comprehensive treatment.On this basis,patients in the observation group were given artificial liver plasmapheresis apparatus to perform plasmapheresis treatment.Comparing the biochemical changes before and after treatment between the two groups,the treatment efficiency of the two groups was compared.Result:Before treatment,there was no significant difference in ALT,AST,ALB,PTA and TBIL between the two groups,P>0.05,have comparability.The improvement of biochemical indexes of the patients after treatment was obviously better than that of the control group,P<0.05,with statistical significance.The total effective rate of the observation group was 85.0%(34/40),significantly higher than the control group of 65.0%(26/40),P<0.05,with statistical significance.Conclusion:Patients with severe hepatitis b were treated with artificial liver plasmapheresis,can effectively improve the liver function of patients,have exact effect.