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血清缺血修饰清蛋白诊断糖尿病肾病的临床意义

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摘要 目的分析血清缺血修饰清蛋白(IMA)对糖尿病肾病(DN)的诊断价值。方法选取150例DN患者作为观察组,选取同期150例健康体检者作为对照组。两组均抽取静脉血进行生化检测与IMA检测,对比两组24 h尿蛋白定量、IMA水平以及DN检出率。结果观察组24 h尿蛋白定量(84.45±11.25)mg/24 h、IMA(75.49±6.32)U/ml均高于对照组的(0.10±0.04)mg/24 h、(68.22±1.02)U/ml,差异有统计学意义(P<0.05)。观察组采用IMA联合糖化血红蛋白(HbA1c)、甘油三酯(TG)的DN检出率为96.67%,与采用24 h尿蛋白定量的98.7%对比,差异无统计学意义(P>0.05)。对照组采用IMA联合生化指标HbA1c、TG的DN检出率为3.33%,与采用24 h尿蛋白定量的2.00%对比,差异无统计学意义(P>0.05)。结论 IMA对糖尿病肾病的诊断价值高,值得推广。
出处 《中国实用医药》 2021年第3期63-65,共3页 China Practical Medicine
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