气相色谱-质谱联用法测定化妆品中的二甘醇

Determination of Diethylene Glycol in Cosmetics by Gas Chromatography/Mass Spectrometry

建立化妆品中二甘醇的气相色谱-质谱联用分析方法,采用DB-WAXETR毛细管柱,样品经无水乙醇超声提取,外标法进行定量。结果表明,二甘醇在1~50 mg/L浓度范围内线性关系良好(r^2=0.9993),方法的检出限为0.03 mg/kg,回收率为104%~112%,相对标准偏差(RSD)为2.1%~4.2%。该方法准确、可靠,适用于化妆品中二甘醇的检测。

The method of Gas Chromatography/Mass Spectrometry was established for diethylene glycol in cosmetics,and adopting the DB-WAXETR capillary column.The sample was ultrasonic extracted with ethanol.It was quantitatived by the external standard method.The results showed that a good linear relationship(r^2=0.9993)in the concentration range of 1~50 mg/L.The limit of detection was 0.03 mg/kg.The recovery was between 104% and 112%,the relative standard deviation(RSD)was 2.1%~4.2%.The method is accurate and reliable,which was suitable for the determination of diethylene glycol in cosmetics.