降钙素原及乳酸水平在脓毒血症中的临床意义

Clinical significance of procalcitonin and lactic acid levels in sepsis

目的:分析降钙素原及乳酸水平在脓毒血症中的应用价值。方法:2018年1月-2020年5月收治脓毒血症患儿40例,依据病情严重程度分为脓毒症组、严重脓毒症组、脓毒性休克组。按照临床治疗终点分为存活组与死亡组。观察不同病情患儿血清中降钙素原与乳酸水平,并对比存活组与死亡组患儿血清降钙素原与乳酸水平。结果:脓毒性休克组患儿降钙素原与乳酸水平明显高于脓毒症组、严重脓毒症组,差异有统计学意义(P<0.05)。存活组患儿降钙素原与乳酸水平显著低于死亡组,差异有统计学意义(P<0.05)。结论:临床可通过降钙素原与乳酸水平对脓毒血症患儿病情进行判断,临床意义重大。

Objective:To explore the clinical significance of procalcitonin and lactic acid levels in sepsis.Methods:From January 2018 to May 2020,40 children with sepsis were selected and divided into the sepsis group,the severe sepsis group and the septic shock group according to the severity of the disease.According to the clinical treatment end point,they were divided into the survival group and the death group.We observed the levels of serum procalcitonin and lactic acid in children with different diseases,and compared the levels of serum procalcitonin and lactic acid between the survival group and the death group.Results:In the septic shock group,the levels of procalcitonin and lactic acid were significantly higher than those in the sepsis group and the severe sepsis group,the difference was statistically significant(P<0.05).In the survival group,the levels of procalcitonin and lactic acid were significantly lower than those in the death group,the difference was statistically significant(P<0.05).Conclusion:Clinically,we can judge the condition of children with sepsis by procalcitonin and lactic acid levels,which is of great clinical significance.