盘龙灸治疗慢性疲劳综合征临床研究

Clinical Study on Yang-Supporting Moxibustion in the Treatment of Chronic Fatigue Syndrome

目的:观察盘龙灸治疗慢性疲劳综合征(chronic fatigue syndrome,CFS)的临床疗效。方法:将80例CFS患者按照随机数字表法分为治疗组和对照组,每组40例。治疗组采用盘龙灸治疗,对照组采用电针治疗。比较两组患者的临床疗效及治疗前后疲劳量表-14、疲劳评定量表评分变化情况,检测两组患者治疗前后白细胞介素-2(interleukin-2,IL-2)、白细胞介素-6(interleukin-6,IL-6)和肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)水平变化情况。结果:两组患者治疗后疲劳量表-14和疲劳评定量表评分低于本组治疗前,且治疗组治疗后低于对照组治疗后,差异均有统计学意义(P<0.05)。两组患者治疗后IL-2高于本组治疗前,且治疗组治疗后高于对照组治疗后;两组患者治疗后IL-6、TNF-α低于本组治疗前,且治疗组治疗后低于对照组治疗后,差异均有统计学意义(P<0.05)。对照组有效率为87.50%,治疗组有效率为95.00%,两组患者有效率比较,差异具有统计学意义(P<0.05)。结论:盘龙灸可能通过抑制IL-6、TNF-α的表达,促进IL-2的表达,调节机体免疫功能,改善CFS患者疲劳状态。

Objective:To observe the clinical curative effect of yang-supporting moxibustion on chronic fatigue syndrome(CFS).Methods:A total of 80 patients with CFS were randomly divided into the treatment group and the control group,with 40 cases in each group.The treatment group was treated with yang-supporting moxibustion,while the control group was treated with electroacupuncture.The clinical efficacy and the changes of fatigue scale-14 and fatigue rating scale before and after treatment were compared between the two groups.The levels of interleukin-2(IL-2),interleukin-6(IL-6) and tumor necrosis factor-α(TNF-α) were detected before and after the treatment.Results:After the treatment,the scores of fatigue scale-14 and fatigue rating scale in the two groups were lower than those of the same group before the treatment,and the scores in the treatment group after the treatment were lower than those in the control group after treatment,and all the differences were statistically significant(P<0.05).After the treatment,IL-2 of the two groups was higher than that of the same group before the treatment,and IL-2 of the treatment group was lower than that of the control group;while IL-6 and TNF-α of the two groups were lower than those of the same group before the treatment,and the above indexes of the treatment group were lower than those of the control group;and all the differences were statistically significant(P<0.05).The effective rate of the control group was 87.50%,while that of the treatment group was 95.00%.The difference between the two groups was statistically significant(P<0.05).Conclusion:Yang-supporting moxibustion may inhibit the expressions of IL-6 and TNF-α,promote the expression of IL-2,regulate the immune function and improve the fatigue state of CFS patients.