摘要
Trehalose is a non-reducing disaccharide, and widespread in nature. It is a typical stress metabolite that can protect macromolecules such as proteins in organisms under extreme conditions. Therefore, trehalose has been widely used in food, medicine and cosmetics. Trehalose is extracted from yeast or synthesized by chemical method. Due to the high cost of traditional methods, trehalose is mainly produced by enzymatic methods. There are mainly three pathways: TPS/TPP, TreY/TreZ and TreS. These enzymatic systems are expressed mainly through heterologous expression.
基金
Supported by National Nature Science Foundation of China(No.32001632)。