网络干预疗法对产后抑郁症治疗效果的Meta分析

Effect of network intervention on postpartum depression:a Meta-analysis

目的:系统评价网络干预措施对产后抑郁症的治疗效果。方法:计算机检索PubMed、the Cochrane Library、EMbase、CINAHL、Web of Science、中国期刊全文数据库(CNKI)、中国生物医学数据库(CBM)、万方数据库(WanFang database)中关于网络干预改善产后抑郁症效果的随机对照试验(RCT),检索时间均为建库至2020年4月14日,筛选文献并提取资料,对符合标准的随机对照试验采用Cochrane风险偏倚评价工具评价文献质量,采用RevMan 5.3进行Meta分析,GRADE进行证据等级质量评价。结果:共纳入10篇RCTs,涉及1 258例病人。Meta分析结果显示:与常规治疗相比,网络干预可缓解产妇的抑郁情绪[SMD=-0.34,95%CI(-0.45,-0.22),P<0.000 01],网络干预可缓解产妇产后焦虑[SMD=-0.20,95%CI(-0.39,-0.02),P=0.03]。GRADE证据等级评价为中等级别证据。结论:现有证据表明网络干预疗法可改善产后抑郁病人的抑郁情绪。

Objective:To systematically evaluate the effect of network intervention on postpartum depression.Methods:Randomized controlled trials(RCTs)on the effect of network intervention in the treatment of postpartum depression were searched from PubMed,the Cochrane Library,EMbase,CINAHL,Web of Science,CNKI,CBM and WanFang database.The retrieval time was from the establishment of the database to April 14,2020.The literatures were screened and the data were extracted.The quality of randomized controlled trials that met the standards was evaluated by Cochrane risk bias assessment tool,and the Meta-analysis was conducted by RevMan 5.3,GRADE was used to evaluate the quality of evidence grade.Results:A total 10 RCTs were included,involving 1258 patients.Mate-analysis results showed that compared with routine treatment,network intervention could relieve maternal depression[SMD=-0.34,95%CI(-0.45,-0.22),P<0.00001],and postpartum anxiety[SMD=-0.20,95%CI(-0.39,-0.02),P=0.03].The GRADE evidence grade is medium-level evidence.Conclusion:The current evidence showed that network intervention therapy could improve the depression of patients with postpartum depression.