急性缺血性脑卒中静脉溶栓后出血性转化危险因素临床观察

Cl inical Observation on Risk Factors of hemorrhagic Transformation after intravenous Thrombolysis in Patients with acute ischemic Stroke

目的分析急性缺血性脑卒中患者在静脉溶栓后发生出血转化与其预后的可能危险因素。方法选择2019年1月至2019年12月在庆阳市人民医院接受静脉溶栓治疗的40例急性缺血性脑卒中患者为研究对象,按照有无出血转化划分为观察组(15例,发生出血转化)和对照组(25例,未发生出血转化)。统计两组溶栓前后的NIHSS评分。结果本研究结果显示,观察组溶栓前及溶栓2 h后的NIHSS评分均显著高于对照组,差异显著(P<0.01)。结论在急性缺血性脑卒中静脉溶栓患者中,溶栓前和溶栓2 h后的NIHSS评分较高是出现出血性转化的危险因素,应做好针对性预防。

Objective To analyze the possible risk factors of hemorrhagic transformation and prognosis in patients with acute ischemic stroke after intravenous thrombolysis.Methods From January 2019 to December 2019,40 patients with acute ischemic stroke received intravenous thrombolytic therapy in Qingyang People's hospital,the patients were divided into observation group(15 cases,had hemorrhagic transformation)and control group(25 cases,had no hemorrhagic transformation).The NIHSS scores before and after thrombolysis were measured.Results The results showed that the NIHSS scores of the observation group were significantly higher than those of the control group(P<0.01).Conclusion Higher NIHSS scores before thrombolysis and 2 hours after thrombolysis are the risk factors of hemorrhagic transformation in patients with acute ischemic stroke,we should do a good job of targeted prevention.