单纯抗凝应用在急性中危肺血栓栓塞症患者治疗中的临床效果

Clinical Effect of Simple Anticoagulation in the Treatment of Patients with Acute Intermediate-risk Pulmonary Thromboembolism

目的分析单纯抗凝方案治疗急性中危肺血栓栓塞症患者的临床效果。方法选择我院收治的急性中微肺血栓栓塞症患者56例作为观察组,另选择同期的56例患者作为对照组,分别进行单纯抗凝治疗和抗凝联合溶栓治疗,比较效果。结果干预后,两组患者治疗总有效率、血气指标(Pa O2、Pa CO2、P(A-a)O2)变化情况、超声心动图相关指标(RVESVI、RVEDVI、RVEF)方面均无显著性差异,P> 0.05;观察组不良反应发生率低于对照组,差异有显著性,P <0.05。结论对急性中危肺血栓栓塞症患者采用单纯抗凝的治疗方案能够在确保治疗安全性的基础上有很好的治疗效果。

Objective To analyze the clinical effect of pure anticoagulant regimen in the treatment of patients with acute intermediate-risk pulmonary thromboembolism. Methods Fifty-six patients with acute medium and micro pulmonary thromboembolism in our hospital were selected as the observation group, and 56 patients during the same period were selected as the control group. The effects were compared with anticoagulation therapy alone and anticoagulation combined with thrombolytic therapy. Results After the intervention, there were no significant differences in the total effective rate of treatment, blood gas indicators(Pa O2, Pa CO2, P(A-a) O2), and echocardiographic related indicators(RVESVI, RVEDVI, RVEF) between the two groups of patients, P >0.05;The incidence of adverse reactions in the observation group was lower than that in the control group, the difference was significant, P<0.05. Conclusion The use of pure anticoagulant therapy for patients with acute intermediate-risk pulmonary thromboembolism can have a good therapeutic effect on the basis of ensuring the safety of treatment.