自拟参芎安神汤治疗不寐临床观察

Clinical observation on treating insomnia with the Shenxiong Anshen decoction

目的:通过自拟参芎安神汤治疗不寐观察其临床疗效。方法:将86例患者随机分为两组,治疗组44例,采用自拟参芎安神汤加味治疗;对照组42例,给予西药地西泮片治疗。结果:治疗组总有效率优于对照组(P <0.05)。治疗前后对比,治疗组在匹兹堡睡眠质量指数(Pittsburgh Sleep Quality Index,PSQI)各因子及中医症状积分均有明显改善,而且治疗组不良反应发生率在嗜睡、恶心、头昏、口干、乏力明显低于对照组(P <0.01)。结论:自拟参芎安神汤治疗不寐疗效显著。

Objective: To observe the clinical efficacy of the Shenxiong Anshen decoction( 参芎安神汤) on insomnia. Methods: 86 cases were randomly divided into two groups. 44 cases in the treatment group took the Shenxiong Anshen decoction, and 42 cases in the control group were treated with diazepam tablets. Results: The total efficiency in the treatment group was better than that in the control group(P<0.05). The PSQI factors and TCM symptom scores after treatment in the treatment group were significantly improved compared with before, and the incidence of adverse reactions in the treatment group was significantly lower than the control group in terms of lethargy, nausea, dizziness, dry mouth and fatigue(P<0.01). Conclusion: The Shenxiong Anshen decoction is effective on insomnia.