泄浊通淋汤联合左氧氟沙星治疗慢性细菌性前列腺炎的临床研究

A clinical study on treating chronic bacterial prostatitis with the Xiezhuo Tonglin decoction plus levofloxacin

目的:探讨泄浊通淋汤联合左氧氟沙星治疗慢性细菌性前列腺炎的临床应用效果。方法:选取2018年5月-2019年4月在我院接受治疗的86例慢性细菌性前列腺炎,按随机数表法分为两组,各43例。给予A组左氧氟沙星治疗,给予B组泄浊通淋汤联合左氧氟沙星治疗。比较两组临床疗效、治疗前后美国国立卫生研究院慢性前列腺炎症状指数(NIH-CPSI)评分、血清炎性因子超敏C反应蛋白(Hypersensitive C-reactive Protein,hs-CRP)及肿瘤坏死因子α(Tumor Necrosis Factor-α,TNF-α)的变化情况。结果:B组治疗有效率较对照A组高,差异有统计学意义(P <0.05);和治疗前相比,治疗后A组和B组NIHCPSI评分、血清hs-CRP、TNF-α水平均降低,且B组较A组低,差异有统计学意义(P <0.05);两组均未出现不良反应。结论:给予慢性细菌性前列腺炎患者泄浊通淋汤联合左氧氟沙星进行治疗,疗效显著,可有效改善临床症状,减轻炎症反应,且不良反应较少,值得推广。

Objective: To explore the clinical effects of the Xiezhuo Tonglin decoction( 泄浊通淋汤) plus levofloxacin on chronic bacterial prostatitis. Methods: 86 cases were divided into two groups according to random number table method, 43 cases in each. Group A was given levofloxacin, and group B took the Xiezhuo Tonglin decoction with levofloxacin. Results: The total efficiency in group B was higher than that in group A(P<0.05). Compared with before treatment, the NIH-CPSI scores, serum hs-CRP, and TNF-α levels in both group were decreased after treatment, and group B was lower than group A(P<0.05). There was no adverse reaction in the groups. Conclusion: The Xiezhuo Tonglin decoction plus levofloxacin on chronic bacterial prostatitis shows significant effects, can effectively improve the clinical symptoms of patients, reduce inflammatory reactions, with fewer adverse reactions, and is worth promoting.