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不同药物注射治疗对膝骨关节炎患者步态的影响 被引量:3

Effects of Different Drug Injection on Gait of Patients with Knee Osteoarthritis
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摘要 目的:探讨超声引导注射不同药物治疗对膝骨关节炎(KOA)患者步态的影响。方法:选取2017年1月~2019年9月本院收治的110例KOA患者作为研究对象,依据随机数字表法分为化药组与中药组,各55例。化药组采用超声引导下膝关节内注射化药治疗,中药组采用超声引导下膝关节内注射中药制剂治疗;治疗1个疗程后观察两组患者疼痛程度、膝关节功能及步态变化情况。结果:治疗后,两组患者视觉模拟(VAS)评分、西部安大略省和麦克马斯特大学骨关节炎指数(WOMAC)、膝关节Lysholm评分、膝关节Lequesne指数均较本组治疗前改善,且中药组优于化药组,有统计学差异(P <0.05);治疗后,两组患者步速、步宽、步态周期、患侧健侧支撑相时间、患侧健侧摆动相时间、双足支撑相时间均较本组治疗前改善,且中药组优于化药组,有统计学差异(P <0.05);治疗后,两组患者步长偏差、健患侧支撑相比值、健患侧摆动相比值均较本组治疗前改善,且中药组优于化药组,有统计学差异(P <0.05)。结论:超声引导下注射治疗KOA可理想地改善患者膝关节功能,对患者步态恢复具有积极影响。 Objective:To investigate the effect of ultrasonic-guided injection of different drugs on gait in patients with knee osteoarthritis(KOA).Methods:From January 2017 to September 2019,110 cases of KOA patients were included in this study,and randomly divided into the chemical drugs and traditional Chinese medicine group according to random number table method.The chemical drugs group was treated with ultrasonic-guided knee joint injection of chemical drugs,while the traditional Chinese medicine group with ultrasonic-guided knee joint injection of TCM.After one course of treatment,the pain degree,joint function and gait changes of the two groups of patients were observed.Results:After treatment,VAS,WOMAC,Lysholm,and Lequesne indexes in the two groups were all improved in both groups compared with before treatment,with more improvement found in the traditional Chinese medicine group(P<0.05).After treatment,the gait speed,stride width,gait cycle,supporting phase time of the healthy side and sick side,swinging phase time of the healthy side and the sick side,and supporting phase time of the double foot in the two groups were all improved compared with before treatment,with more improvement found in the traditional Chinese medicine group(P<0.05).After treatment,the deviation of step size,the relative value of the healthy side support versus the sick side support and the relative value of the healthy side swing versus the sick side swing in the two groups were all improved compared with before treatment,with more improvement found in the traditional Chinese medicine group(P<0.05).Conclusion:Ultrasound-guided injection in the treatment of knee osteoarthritis can improve knee joint function and have a positive effect on gait recovery.
作者 黄长安 亢军义 喻景奕 HUANG Chang-an;KANG Jun-yi;YU Jing-yi(Spine Surgery,Chushi Orthopaedic Hospital,Huaiyang,Zhoukou 466723,China;Spine Surgery,Zhoukou Central Hospital,Zhoukou 466000,China)
出处 《中国合理用药探索》 CAS 2021年第1期60-63,共4页 Chinese Journal of Rational Drug Use
关键词 膝骨关节炎 关节内注射 超声 步态 关节功能 knee osteoarthritis intra-articular injection ultrasonic gait joint function
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