中国反常性痤疮/化脓性汗腺炎诊疗专家共识(2021版)

Diagnosis and treatment of acne inversa/hidradenitis suppurativa in China:an expert consensus statement(2021 version)

反常性痤疮(AI)/化脓性汗腺炎(HS)是一种因毛囊闭锁导致毛囊皮脂腺单位受累的慢性复发性炎症性皮肤病,好发于顶泌汗腺分布区域,主要表现为青春期开始出现的疼痛性、深在性、炎症性皮损。AI/HS发病与遗传、炎症与免疫、微生物、肥胖及吸烟等因素相关。AI/HS治疗困难,目前的治疗以控制皮损发作频率和发作持续时间、提高患者生活质量为主。医生应根据病情严重程度分级治疗,药物治疗包括抗生素、维A酸类、生物制剂、免疫抑制剂以及抗雄激素药物等,辅助治疗包括外科手术或光电治疗。该共识旨在进一步规范中国AI/HS诊断与治疗方法,提高诊疗水平。

Acne inversa(AI)/hidradenitis suppurativa(HS)is a chronic,recurrent,inflammatory skin disease that centers on the hair follicular unit because of follicular occlusion.It mainly presents as painful,deep-seated,inflamed lesions since puberty,and most commonly occurs in the apocrine gland-bearing areas.The etiology and pathogenesis of AI/HS involve internal and external factors,such as genetic susceptibility,inflammation and immunity,microorganisms,obesity and smoking.Treatment of AI/HS is difficult,and the current aim of treatment is to control the frequency and duration of disease flares and improve the quality of life.Treatment protocols of AI/HS should be based on the disease severity grade.Medical treatments include antibiotics,retinoids,biologics,immunosuppressive agents,antiandrogen agents,and so on,and adjuvant treatments include surgery and laser/light therapies.This consensus aims to further standardize the diagnosis and treatment procedures of AI/HS in China,so as to facilitate its diagnosis and treatment.