中国黄褐斑诊疗专家共识(2021版)

Consensus on diagnosis and treatment of melasma in China(2021 version)

目前认为黄褐斑的发病与遗传、日光、性激素等有关,涉及黑素合成增加、皮损处血管增生、炎症反应及皮肤屏障受损等机制。诊断主要依据临床表现和无创检测技术。该指南结合近年研究新进展,全面阐述了黄褐斑的病因及发病机制、临床表现、分期与分型、诊断及治疗等,旨在提高中国皮肤科医师对黄褐斑的诊治水平。

At present,exact pathogenesis of melasma remains unclear,genetics,sunlight exposure,sex hormones,etc.,are considered as the main causative factors.Its pathogenesis involves excessive melanin synthesis,vascular hyperplasia in skin lesions,inflammation and skin barrier impairment.The diagnosis of melasma mainly relies on clinical manifestations and non-invasive detection techniques.Based on research progress in recent years,this consensus comprehensively elaborates the etiology,pathogenesis,clinical manifestations,staging and classification,diagnosis and treatment of melasma,aiming to improve the diagnosis and treatment of melasma by Chinese dermatologists.