比较氯卡色林与阿卡波糖片对肥胖症患者血脂水平的影响

A comparative study of the effects of lorcaserin and acarbose tablets on blood lipid levels in obesity patients

目的比较氯卡色林与阿卡波糖片对肥胖症患者血脂水平的影响。方法选取该院2018年1月至2019年3月收治的110例肥胖症患者为研究对象,按照随机数字表法分为氯卡色林组及阿卡波糖片组,每组55例,前者采用氯卡色林治疗,后者采用阿卡波糖片治疗,6个月后对两组体质量相关指标、血脂水平、不良反应发生率进行比较。结果治疗前两组体质量相关指标、血脂水平比较,差异无统计学意义(P>0.05);治疗后两组以上指标均较治疗前明显改善,差异有统计学意义(P<0.05),两组间比较,差异无统计学意义(P>0.05);氯卡色林组的不良反应发生率(12.73%)与阿卡波糖片组(14.55%)比较,差异无统计学意义(χ2=0.141,P=0.708)。结论氯卡色林与阿卡波糖片均能够在肥胖症治疗中取得良好疗效,且有助于调节血脂水平,改善患者健康水平。

Objective To compare the effects of lorcaserin and acarbose tablets on blood lipid levels in obesity patients.Methods A total of 110 cases of obesity patients admitted in Huludao Central Hospital from January 2018 to March 2019 were selected as the subjects and divided into lorcaserin group(treated with lorcaserin)and acarbose group(treated with acarbose)according to the random number table method,55 cases in each group.The body weight-related indexes,blood lipid levels,and incidence of adverse reactions were compared in the two groups after teatment 6 months.Results There was no statistically significant difference on body weight-related indexes and blood lipid levels between the two groups before treatment(P>0.05).After treatment,these indicators significantly improved compared with those before treatment,the differences were statistically significant(P<0.05),with no statistically significant difference between the two groups(P>0.05).The incidence of adverse reaction in lorcaserin group(12.73%)had no significant difference with acarbose group(14.55%,χ2=0.141,P=0.708).Conclusion Both lorcaserin and acarbose tablets could achieve good results in the treatment of obesity and help to regulate blood lipid levels and improve patients′health.