摘要
L-木酮糖是自然界罕见的L-型戊酮糖,具有糖苷酶抑制活性能够降低血糖,还可以用作医药中间体。L-木酮糖仅能通过人工合成来大量获得,常用的方法包括利用氧化还原酶催化木糖醇或L-阿拉伯糖醇等。近年来L-木酮糖的生物制备技术获得了较为广泛的研究,文章针对L-木酮糖制备关键酶挖掘、制备工艺探索等内容进行了综述,以期为该领域的研究提供理论借鉴。
L-Xylulose is a rarely L-form pentose,and is able to inhibit the activities of glycosidases for the purpose of controlling human blood sugar levels.It is also useful as a pharmaceutical intermediate.Currently,L-xylulose can only be obtained by artificial synthesis,such as enzymatic catalysis targeting xylitol or L-arabinitol by oxidoreductases.In recent years,bio-production procedure of L-xylulose has been extensively studied.This review focuses on investigations of key enzymes for L-xylulose production,as well as the production processes,to provide theoretical references for relative research in this field.
作者
徐铮
刘雅知
潘森皓
李光耀
XU Zheng;LIU Yazhi;PAN Senhao;LI Guangyao(College of Food Science and Light Industry,State Key Laboratory of Materials-Oriented Chemical Engineering,Nanjing Tech University,Nanjing 211816,China)
出处
《食品与发酵工业》
CAS
CSCD
北大核心
2021年第3期205-210,共6页
Food and Fermentation Industries
基金
江苏省六大人才高峰项目(NY-056)。
关键词
L-木酮糖
稀少糖
功能糖
酶催化
木糖醇
L-xylulose
rare sugar
functional sugar
enzymatic catalysis
xylitol
