地西泮联合缩宫素对产程潜伏期延长倾向产妇产程及妊娠结局的影响

Effect of Diazepam Combined with Oxytocin on Labor Process and Pregnancy Outcome of Pregnant Women with Prolonged Latent Labor Duration

【目的】探讨地西泮联合缩宫素对产程潜伏期延长倾向产妇产程及妊娘结局的影响。【方法】回顾性分析2017年3月至2018年3月在本院分娩的300例有产程潜伏期延长倾向的产妇的临床资料。根据治疗方式的不同分为观察组和对照组,每组150例。观察组采用地西泮联合缩宫素治疗,对照组仅采用缩宫素治疗。比较两组产妇的宫颈和产程情况(宫口全开时间、宫口扩张速度、第一产程时间和第二产程时间)和妊娠结局(阴道分娩率、宫颈水肿率和裂伤率、胎儿窘迫发生率和产后2 h出血量)。并于分娩结束后24 h采用生活质量(QOL)评分评估两组产妇生活质量。【结果】观察组用药后宫口全开时间、第一产程和第二产程时间均显著短于对照组,宫口扩张速度大于对照组,差异有统计学意义(P<0.05)。观察组阴道分娩率显著高于对照组,宫颈水肿率、宫颈裂伤率、胎儿窘迫发生率和产后2 h出血量均低于对照组,差异有统计学意义(P<0.05)。产后12 h,观察组的QOL评分显著高于对照组,差异有统计学意义(P<0.05)。【结论】地西泮联合缩宫素应用于产程潜伏期延长倾向的产妇,可加速产程进展,改善妊娠结局,提高产妇生活质量,值得临床推广应用。

【Objective】To explore the effect of dirizepam combined witli oxytocin on labor process and pregnancy outcome of pregnant women with prolonged latency tendency.【Methods】The clinical data of 300 cases of maternal diagnosis and treatment with a tendency to prolong the incubation period in our hospital from March 2017 to March 2018 were analyzed retrospectively.According to different treatment methods,patients were divided into two groups,150 in each group.The observation group was treated with diazepam and oxytocin,and the control group was only treated with oxytocin.The cervix and labor status(total opening time of uterine orifice,dilatation rate,first stage of labor and second stage of labor),pregnancy outcome(vaginal delivery rate,cervical edema rate and laceration rate,incidence of fetal distress and postpartum 2h bleeding),and the Quality of Life(QOL)score at 24 hours postpartum were compared between the two groups.【Results】The uterine ostium total upening time,the first stage of labor and the second stage of labor in the observation group were significantly shorter than those of the control group,and the dilatation rate of the uterine orifice was significantly faster than that of the control group(P<0.05).The vaginal delivery rate of the observation group was significantly higher than that of the control group,and the cervical edema rate,cervical laceration rate,the incidence of fetal distress and the amount of postpartum hemorrhage were lower than those of the control group(P<0.05).The QOL score of the observation group was statistically higher than that of the control group postpartum 24h(P<0.05).【Conclusion】Diazepam romhined with oxytocin can accelerate the progress of labor,improve pregnancy uutcome,raise QOL score and improve the quality of life of women with prolonged latency tendency.