促卵泡方对未破裂卵泡黄素化综合征致不孕患者周期排卵率及临床妊娠率的影响

Effect of Follicle-stimulating Recipe on Periodic Ovulation Rate and Clinical Pregnancy Rate for Patients with Infertility Caused Byluteinized Unruptured Follicle Syndrome

目的:观察未破裂卵泡黄素化综合征致不孕患者采用中药促卵泡方对其周期排卵率、临床妊娠率的影响作用。方法:选取2018年8月~2019年8月本院收治的70例未破裂卵泡黄素化综合征致不孕患者,随机数字表法将患者分为观察组和对照组,各35例。对照组患者给予人绒毛膜促性腺激素治疗,观察组在此基础上加以中药促卵泡方治疗,比较两组周期排卵、临床妊娠、未破裂卵泡黄素化综合征复发情况。结果:观察组临床治疗总有效率82.86%显著高于对照组的60.00%(P<0.05);观察组观察94个周期,排卵率为61.70%(58/94),对照组观察93个周期,排卵率为36.56%(34/93),两组排卵率比较差异有统计学意义(P<0.05);观察组妊娠率45.71%明显高于对照组的14.29%(P<0.05);观察组未破裂卵泡黄素化综合征复发率34.04%明显低于对照组的59.14%,两组复发率比较差异有统计学意义(P<0.05)。结论:对未破裂卵泡黄素化综合征致不孕患者给予中药促卵泡方治疗临床效果显著,可有效提高患者周期排卵率和妊娠率,降低未破裂卵泡黄素化综合征复发率,可推广应用。

Objective: To investigate the effect of Follicle-stimulating Recipe on the periodic ovulation rate and clinical pregnancy rate for patients with infertility caused by luteinized unruptured follicle syndrome.Methods: 70 patients with infertility caused by luteinized unruptured follicle syndrome who were admitted to the hospital between August 2018 and August 2019 were selected.They were divided into observation group and controlled group by the random number table method, with 35 cases in each group.Patients in the controlled group were treated with human chorionic gonadotropin.On this basis, the observation group were treated with traditional Chinese medicine Follicle-stimulating Recipe.The periodic ovulation rate, clinical pregnancy rate and recurrence of luteinized unruptured follicle syndrome were compared between the two groups.Results: The total effective rate of clinical treatment in the observation group(82.86%) was significantly higher than that in the controlled group(60.00%)(P < 0.05).The observation group were observed for 94 cycles and the ovulation rate was 61.70%(58/94),while the controlled group were observed for 93 cycles and the ovulation rate was 36.56%(34/93)(P < 0.05).The pregnancy rate of the observation group(45.71%) was significantly higher than that of the controlled group(14.29%)(P < 0.05).The recurrence rate in the observation group(34.04%) was significantly lower than that in the controlled group(59.14%)(P < 0.05).Conclusion: Using traditional Chinese medicine Follicle-stimulating Recipe is markedly effective in the treatment of patients with luteinized unruptured follicle syndrome.It can effectively improve the periodic ovulation rate and pregnancy rate, and reduce the recurrence rate.